Chris,

The WOW64 subsystem isolates the execution of 32-bit applications from 64-bit applications. That means, Windows 64-bit (XP up to Server 2012 R2) always (and not sometimes) redirects to the "WOW6432node". But this does not cause problems (it's expected and by Windows design).

If you create a 32-bit type install for your 32-bit application and you install into the correct folder then it is not caused by redirection at all. Make sure that you request administrator execution level privileges ("requireAdministrator") and that your ActiveX does not rely on missing dependency files.

Hope this helps a bit.

Friedrich